Year | Citation |
---|---|
2018 |
Cooke, M. B., Rybalka, E., Stathis, C. G., & Hayes, A. (180501). Myoprotective potential of creatine is greater than whey protein after chemically-induced damage in rat skeletal muscle. Nutrients, 10(5), doi: 10.3390/nu10050553 |
2017 |
Hanson, E. D., Nelson, A. R., West, D. WD., Violet, J. A., O'Keefe, L., Phillips, S. M., & Hayes, A. (170301). Attenuation of resting but not load-mediated protein synthesis in prostate cancer patients on androgen deprivation. Journal of Clinical Endocrinology and Metabolism, 102(3), (1076-1083). doi: 10.1210/jc.2016-3383 |
2015 | Timpani, C. A., Hayes, A., & Rybalka, E. (151201). Revisiting the dystrophin-ATP connection: How half a century of research still implicates mitochondrial dysfunction in Duchenne Muscular Dystrophy aetiology. Medical Hypotheses, 85(6), (1021-1033). |
2014 | Rybalka, E., Timpani, C. A., Cooke, M. B., Williams, A. D., & Hayes, A. (141226). Defects in mitochondrial ATP synthesis in dystrophin-deficient Mdx skeletal muscles may be caused by complex I insufficiency. PLoS ONE, 9(12), |
2014 | Scott, D., Hayes, A., Sanders, K. M., Aitken, D., Ebeling, P. R., & Jones, G. (140101). Operational definitions of sarcopenia and their associations with 5-year changes in falls risk in community-dwelling middle-aged and older adults. Osteoporosis International, 25(1), (187-193). |
2008 | Williams, A. D., Cribb, P. J., Cooke, M. B., & Hayes, A. (080101). The effect of ephedra and caffeine on maximal strength and power in resistance-trained athletes. Journal of Strength and Conditioning Research, 22(2), (464-470). |
2007 | Cribb, P. J., Williams, A. D., Stathis, C. G., Carey, M. F., & Hayes, A. (070201). Effects of whey isolate, creatine, and resistance training on muscle hypertrophy. Medicine and Science in Sports and Exercise, 39(2), (298-307). |
2006 | Cribb, P. J., & Hayes, A. (061101). Effects of supplement timing and resistance exercise on skeletal muscle hypertrophy. Medicine and Science in Sports and Exercise, 38(11), (1918-1925). |
1996 | Hayes, A., & Williams, D. A. (960101). Beneficial effects of voluntary wheel running on the properties of dystrophic mouse muscle. Journal of Applied Physiology, 80(2), (670-679). |
Key details
Areas of expertise
- muscular dystrophy
- Muscle wasting in cancer induced cachexia and aging sarcopenia
- Dietary supplementation
- Exercise/muscle physiology
- Clinical exercise science – metabolic function & muscle mass & neuromuscular function
Available to supervise research students
Available for media queries
About Alan Hayes
Professor Alan Hayes is the Deputy Director of the Australian Institute for Musculoskeletal Sciences (AIMSS) and has made a number of important contributions to the application of exercise and dietary supplements in muscle disease and dysfunction.
Current projects focus on:
- effects of dietary supplements on skeletal muscle
- improving ageing muscle & developing models of sarcopenia
- delaying severity and/or improving function in muscular dystrophy
- reducing the impact of sarcopenia and prostate cancer with exercise.
Alan was one of the first to examine exercise in models of Duchenne muscular dystrophy demonstrating beneficial effects, even in older animals. He was the first person to explore the potential therapeutic benefits of b2-agonists (such a clenbuterol) as a treatment for muscular dystrophy, sparking a wave of research into other b2-agonists, and other anabolic compounds as treatment strategies for muscular wasting conditions.
In 1997 Alan began his career at Victoria University (VU) and received a Vice Chancellor’s Citation for Teaching Excellence in 2000. He expanded his research to be inclusive of the importance of muscle mass and function in a variety of health conditions, becoming Head of the Exercise Metabolism Unit in 2003.
Alan published seminal papers on the effect of the timing of protein supplementation on resistance exercise-induced increases in skeletal muscle mass and strength. This work won a Victorian State Government award for Applied Research.
Professor Hayes was one of the first to propose, and then directly demonstrate, that mitochondria are a major contributor to the deleterious phenotype of muscular dystrophy, with this research leading to the commencement of numerous clinical trials addressing mitochondrial dysfunction and metabolic dysfunction in various myopathies.
Alan played a pivotal role in designing a unique three-way research partnership between The University of Melbourne (UoM), VU and Western Health at Sunshine Hospital.
He was awarded the Vice Chancellor’s Citation for Research Excellence in Research Supervision in 2011, made an Honorary Associate Professor with the Department of Medicine at UoM in 2016 and promoted to Professor at VU in 2017.
His recent work has shed light on our understanding of the complex interplay between protein synthesis and muscle wasting in human prostate cancer patients. His current work focuses on the risk factors associated with the loss of bone mass, muscle mass and muscle strength with ageing that is leading to new treatment options and/or or prevention strategies.
Qualifications
- PhD, The University of Melbourne, Australia, 1995
- BSc(Hons), The University of Melbourne, Australia, 1991
Key publications
Alan has over 251 publications, with a selection listed here.
A more comprehensive list of Alan's publications is available in the VU Research Repository.
Book (showing 1 of 1)
Year | Citation |
---|---|
2010 | Williams, A. D., Capitanio, N., & Hayes, A. (100101). Skeletal muscle in heart failure and type 2 diabetes. |
Journal article (showing 9 of 177)
Research funding for the past 5 years
Please note:
- Funding is ordered by the year the project commenced and may continue over several years.
- Funding amounts for contact research are not disclosed to maintain commercial confidentiality.
- The order of investigators is not indicative of the role they played in the research project.
2023
Slow
Whey: New options for functional foods targeted at preventing muscle loss–
Phase 3
From: Inner Mongolia Yili Industrial Group, Victoria University
Other investigators: Prof Todor Vasiljevic, Prof Andrew Mcainch
For period: 2023-2023
|
Not disclosed |
2022
Improving Assessment Across the Sciences Using an Assessment Framework
From: Australian Council of Deans of Science
Other investigators: Prof Katerina Tangalakis
For period: 2022-2023
|
$29,734 |
Osteopathic
management of non-specific neck pain: case series
From: Osteopathy Australia Research Fund
Other investigators: Mr Brett Vaughan, Mr Michael Fleischmann, Aspr Patrick Mclaughlin
For period: 2022-2024
|
$9,250 |
2021
Targeting fatty acid metabolism and fat accumulation as a potential therapy in Duchenne Muscular Dystrophy
From: Boehringer Ingelheim International GmbH (Germany)
For period: 2021-2022
|
Not disclosed |
2020
High-intensity interval exercise (HIIE) at lower intensity under hypoxia is able to trigger similar molecular
signalling to induce human muscle protein turnover as HIIE at higher intensity under normoxia.
From: Australian Institute for Musculoskeletal Science (AIMSS)
Other investigators: Dr Xu Yan
For period: 2020-2021
|
$10,000 |
The Roles of Fat Infiltration into Muscle and Lipotoxicity in the Progression of Muscular Dystrophies
From: Australian Institute for Musculoskeletal Science (AIMSS)
For period: 2020-2021
|
$15,000 |
2018
Intense Exercise for survival among men with metastatic castrate-resistant prostate cancer (Interval - MCRPC)
From: Movember Foundation
For period: 2018-2020
|
Not disclosed |
Acknowledgements
Many thanks to the following organisations for their support and essential contributions to my research:
- Uniting AgeWell
Supervision of research students at VU
Available to supervise research students
Available for media queries
Currently supervised research students at VU
No. of students | Study level | Role |
---|---|---|
3 | Master of Applied Research | Principal supervisor |
6 | PhD | Principal supervisor |
2 | PhD | Associate supervisor |
1 | PhD Integrated | Associate supervisor |
Currently supervised research students at VU
Students & level | Role |
---|---|
Master of Applied Research (3) | Principal supervisor |
PhD (6) | Principal supervisor |
PhD (2) | Associate supervisor |
PhD Integrated (1) | Associate supervisor |
Completed supervision of research students at VU
No. of students | Study level | Role |
---|---|---|
12 | PhD | Principal supervisor |
7 | PhD | Associate supervisor |
2 | Masters by Research | Principal supervisor |
1 | Master of Applied Research | Associate supervisor |
1 | Master of Applied Research | Principal supervisor |
Completed supervision of research students at VU
Students & level | Role |
---|---|
PhD (12) | Principal supervisor |
PhD (7) | Associate supervisor |
Masters by Research (2) | Principal supervisor |
Master of Applied Research (1) | Associate supervisor |
Master of Applied Research (1) | Principal supervisor |
Other supervision of research students
Teaching activities & experience
Alan is the Course Chair of Honours in Biomedical Sciences (SHBM).
Alan is Unit Coordinator of the following units:
- HBM3104 Exercise is Medicine
- HBM3203 Integrative Physiology
- RBM2800 Cardiorespitaory and Renal Physiology
- RBM3264 Advanced Nerve and Muscle Physiology
Key academic roles
Dates | Role | Department / Organisation |
---|---|---|
Dec 2016 - Present |
Deputy Director
|
Australian Institute for Musculoskeletal Science (AIMSS) |
Jan 2010 - Mar 2019 |
Assistant Dean
|
Victoria University |
Feb 2014 - Mar 2019 |
Chair, Animal Ethics Committee
|
Victoria University |
Jan 2009 - Dec 2010 |
Academic Coordinator Research and Research Training
|
Victoria University |
Jan 2004 - May 2007 |
Head of School of Biomedical Sciences
|
Victoria University |
Jan 2003 - Dec 2009 |
Head, Exercise Metabolism Unit
|
Victoria University |
Dates | Role & Department/Organisation |
---|---|
Dec 2016 -
Present
|
Deputy Director
Australian Institute for Musculoskeletal Science (AIMSS) |
Jan 2010 -
Mar 2019
|
Assistant Dean
Victoria University |
Feb 2014 -
Mar 2019
|
Chair, Animal Ethics Committee
Victoria University |
Jan 2009 -
Dec 2010
|
Academic Coordinator Research and Research Training
Victoria University |
Jan 2004 -
May 2007
|
Head of School of Biomedical Sciences
Victoria University |
Jan 2003 -
Dec 2009
|
Head, Exercise Metabolism Unit
Victoria University |
Key industry, community & government roles
Dates | Role | Department/Organisation |
---|---|---|
Jan 2018 - Mar 2019 |
Chair, Human Research Ethics Committee
|
National Institute of Integrative Medicine |
Dates | Role & Department/Organisation |
---|---|
Jan 2018 - Mar 2019 |
Chair, Human Research Ethics Committee
National Institute of Integrative Medicine |
Awards
Year | Award |
---|---|
2011 |
Vice Chancellor’s Citation for Research Excellence in Research Supervision - Victoria University |
2004 |
Sport and Recreation Industry award for Applied Research in Sport - Victorian Government |
Keynote and invited speeches
Year | Title/Description |
---|---|
2013 |
Dairy protein intake and resistance exercise for the prevention of sarcopenia in elderly people. International Dairy Federation: World Dairy Summit, Yokohama, Japan |
Professional memberships
- Member, American College of Sports Medicine
- Membership Officer, Australian and New Zealand Society for Sarcopenia and Frailty Research
- Member, American Physiological Society
- Member, American Society for Nutrition
- Member, Australian Physiological Society
- Academic Member, Exercise and Sports Science Australia