Section: Overview
Overview
Key publications
Research funding
Supervising & teaching
Career

Key details

Areas of expertise

  • Epigenetics and adaptation to exercise in health and disease
  • Proteomics
  • Bioinformatics
  • OMICs

Available to supervise research students

Available for media queries

About Macsue Jacques

Dr Jacques has a PhD on the epigenetic basis for variable response to exercise training in humans. During her PhD, she conducted multiple wet-lab and bioinformatics analyses such as DNA methylation and Proteomics in skeletal muscle from humans. 

In July 2021, Dr Jacques was appointed as a Postdoctoral Fellow in Prof Nir Eynon’s laboratory at 1.0 FTE, at the Institute for Health and Sport (iHeS), Victoria University (VU). She have already published 17 manuscripts (four as first author, three as second author, and 10 as co-author) in high-impact peer-reviewed journals (e.g. FASEB J; J Cachexia, Sarcopenia, Muscle; Aging), 3 book chapters (all as first author), and has 2 additional first author articles under review. Her outstanding academic publication record relative to opportunity led to 185 citations (04/11/2021) and her i10 index is 7, meaning that 7 of her publications have been cited > 10 times. Dr Jacques h-index = 8 (Google scholar), and is expected to exponentially increase given the very short time since her first publications.

During her PhD trajectory she was successful in the following travel grants providing an overall AU$3500 support to attend international conferences in the topic of molecular biology: The physiological society Travel grant in 2017, Cells 2019, SECOMB 2019, and The physiological society Travel grant 2019. She was also awarded $300 for the best flash-talk at the Australian Epigenetics Conference 2021.

Her academic leadership is exemplified by being recently elected as the Australian Physiological Society council member. During her PhD she was highly involved in leadership positions such as Student Council member at the HDR committee and Australian physiological society. Dr Jacques has also been involved in facilitating a number of student events and in the organising committee of conferences including: Epigenetics 2021 (virtual), AuPS online student/ECR event 2020, ECR and student workshop for the AuPS conference 2019 and iHeS HDR conference 2018. 

Qualifications

  • PhD, Victoria University, Australia, 2021

Key publications

Year Citation
2024 Grolaux, R., Jones-Freeman, B., Jacques, M., & Eynon, N. (240101). The benefits of exercise on aging: focus on muscle biomarkers. Aging, 16(15), (11482-11483).

doi: 10.18632/aging.206064

2024 Voisin, S., Seale, K., Jacques, M., Landen, S., Harvey, N. R., Haupt, L. M., Griffiths, L. R., Ashton, K. J., Coffey, V. G., & Thompson, J. LM. (240101). Exercise is associated with younger methylome and transcriptome profiles in human skeletal muscle. Aging Cell, 23(1),

doi: 10.1111/acel.13859

2023 Hiam, D., Landen, S., Jacques, M., Voisin, S., Lamon, S., & Eynon, N. (231201). Muscle miRNAs are influenced by sex at baseline and in response to exercise. BMC Biology, 21(1),

doi: 10.1186/s12915-023-01755-3

2023 Landen, S., Jacques, M., Hiam, D., Alvarez-Romero, J., Schittenhelm, R. B., Shah, A. D., Huang, C., Steele, J. R., Harvey, N. R., & Haupt, L. M. (231201). Sex differences in muscle protein expression and DNA methylation in response to exercise training. Biology of Sex Differences, 14(1),

doi: 10.1186/s13293-023-00539-2

2023 Feehan, J., Jacques, M., Kondrikov, D., Eynon, N., Wijeratne, T., Apostolopoulos, V., Gimble, J. M., Hill, W. D., & Duque, G. (231101). Circulating Osteoprogenitor Cells Have a Mixed Immune and Mesenchymal Progenitor Function in Humans. Stem Cells, 41(11), (1060-1075).

doi: 10.1093/stmcls/sxad064

2023 Jacques, M., Landen, S., Romero, J. A., Hiam, D., Schittenhelm, R. B., Hanchapola, I., Shah, A. D., Voisin, S., & Eynon, N. (231001). Methylome and proteome integration in human skeletal muscle uncover group and individual responses to high-intensity interval training. FASEB Journal, 37(10),

doi: 10.1096/fj.202300840RR

2023 Landen, S., Hiam, D., Voisin, S., Jacques, M., Lamon, S., & Eynon, N. (230201). Physiological and molecular sex differences in human skeletal muscle in response to exercise training. Journal of Physiology, 601(3), (419-434).

doi: 10.1113/JP279499

2023 Moreland, E., Cheung, A. S., Hiam, D., Nolan, B. J., Landen, S., Jacques, M., Eynon, N., & Jones, P. (230101). Implications of gender-affirming endocrine care for sports participation. Therapeutic Advances in Endocrinology and Metabolism, 14

doi: 10.1177/20420188231178373

2023 Jacques, M., Landen, S., Romero, J. A., Yan, X., Hiam, D., Jones, P., Gurd, B., Eynon, N., & Voisin, S. (230101). Implementation of multiple statistical methods to estimate variability and individual response to training. European Journal of Sport Science, 23(4), (588-598).

doi: 10.1080/17461391.2022.2048894

2023 Alvarez-Romero, J., Laguette, M. JN., Seale, K., Jacques, M., Voisin, S., Hiam, D., Feller, J. A., Tirosh, O., Miyamoto-Mikami, E., & Kumagai, H. (230101). Genetic variants within the COL5A1 gene are associated with ligament injuries in physically active populations from Australia, South Africa, and Japan. European Journal of Sport Science, 23(2), (284-293).

doi: 10.1080/17461391.2021.2011426

Research funding for the past 5 years

Funding details for this researcher are currently unavailable.

Supervision of research students at VU

Available to supervise research students

Available for media queries

Careers

Details of this Researcher's career are currently unavailable.