Section: Overview
Overview
Key publications
Research funding
Supervising & teaching
Career

Key details

Areas of expertise

  • Exercise physiology
  • Skeletal muscle adaptations to training
  • Acute skeletal muscle responses to exercise
  • Concurrent exercise & training
  • Nutrition for training adaptations and performance

Available to supervise research students

Available for media queries

About Matthew Lee

Dr Matt Lee is an early career researcher with a background in sport science, exercise and muscle physiology, sports nutrition and exercise metabolism. His research broadly involves studying the molecular responses and physiological adaptations to different exercise and training interventions, plus nutritional strategies that support adaptations and performance. 

After completing his undergraduate and master's degrees at Liverpool John Moores University (UK), Dr Lee moved to Australia in 2015 to complete his PhD at Victoria University. His thesis investigated concurrent training (i.e., combined endurance and resistance training), specifically exploring the impact of endurance training on the molecular and physiological adaptations to resistance training, as well as the effect of exercise order.

After being awarded his PhD in 2019, Dr Lee was recruited as a post-doc to lead an industry-funded research collaboration with the Australian Defence Force (ADF). This research project, titled "Optimised Nutrition to Fuel a Fit Soldier", aims to quantify the unique energy demands of ADF personnel. Through a series of field- and laboratory-based studies, combined with existing sports nutrition recommendations, this project seeks to establish specific nutritional strategies and recommendations to maximise training adaptations and performance in ADF personnel. You can read more about one of the current lab-based performance nutrition studies here.

Dr Lee has also collaborated on other projects with both domestic and international researchers, and has publications related to exercise-induced mitochondrial biogenesis, gene expression, myofibrillar and sarcoplasmic protein synthesis, sleep restriction, carbohydrate and hydration for endurance performance, as well as concurrent training adaptations.

Dr Lee also has an interest in science communication, and in 2018 won Victoria University's first "Visualise Your Thesis" showcase, in which he produced a short, 1-min video summarising his PhD research. Dr Lee is also on the Victorian Muscle Network committee, which organises an annual symposium to showcase muscle-related research being conducted throughout Victoria.

Qualifications

  • BSc (Hons), Liverpool John Moores University, UK, 2012
  • MSc, Liverpool John Moores University, UK, 2013
  • PhD, Victoria University, Australia, 2019

Key publications

Year Citation
2024 Diaz-Lara, J., Reisman, E., Botella, J., Probert, B., Burke, L. M., Bishop, D. J., & Lee, M. J. (241001). Delaying post-exercise carbohydrate intake impairs next-day exercise capacity but not muscle glycogen or molecular responses. Acta Physiologica, 240(10),

doi: 10.1111/apha.14215

2024 Lee, M. JC., Saner, N. J., Ferri, A., Garcia-Dominguez, E., Broatch, J. R., & Bishop, D. J. (240601). Delineating the contribution of ageing and physical activity to changes in mitochondrial characteristics across the lifespan. Molecular Aspects of Medicine, 97

doi: 10.1016/j.mam.2024.101272

2024 Saner, N. J., Lee, M. JC., Pitchford, N. W., Broatch, J. R., Roach, G. D., Bishop, D. J., & Bartlett, J. D. (240401). The effect of sleep restriction, with or without high-intensity interval exercise, on behavioural alertness and mood state in young healthy males. Journal of Sleep Research, 33(2),

doi: 10.1111/jsr.13987

2024 Lee, M. J., Caruana, N. J., Saner, N. J., Kuang, J., Stokes, T., McLeod, J. C., Oikawa, S. Y., Bishop, D. J., Bartlett, J. D., & Phillips, S. M. (240101). Resistance-only and concurrent exercise induce similar myofibrillar protein synthesis rates and associated molecular responses in moderately active men before and after training. FASEB Journal, 38(1),

doi: 10.1096/fj.202302024R

2023 Bishop, D. J., Hoffman, N. J., Taylor, D. F., Saner, N. J., Lee, M. JC., & Hawley, J. A. (231101). Discordant skeletal muscle gene and protein responses to exercise. Trends in Biochemical Sciences, 48(11), (927-936).

doi: 10.1016/j.tibs.2023.08.005

2022 Lin, W., Saner, N. J., Weng, X., Caruana, N. J., Botella, J., Kuang, J., Lee, M. JC., Jamnick, N. A., Pitchford, N. W., & Garnham, A. (220722). The Effect of Sleep Restriction, With or Without Exercise, on Skeletal Muscle Transcriptomic Profiles in Healthy Young Males. Frontiers in Endocrinology, 13

doi: 10.3389/fendo.2022.863224

2022 Kuang, J., McGinley, C., Lee, M. JC., Saner, N. J., Garnham, A., & Bishop, D. J. (220204). Interpretation of exercise-induced changes in human skeletal muscle mRNA expression depends on the timing of the post-exercise biopsies. PeerJ, 10

doi: 10.7717/peerj.12856

2022 Kuang, J., Saner, N. J., Botella, J., Lee, M. JC., Granata, C., Wang, Z., Yan, X., Li, J., Genders, A. J., & Bishop, D. J. (220201). Assessing mitochondrial respiration in permeabilized fibres and biomarkers for mitochondrial content in human skeletal muscle. Acta Physiologica, 234(2),

doi: 10.1111/apha.13772

2021 Saner, N. J., Lee, M. JC., Kuang, J., Pitchford, N. W., Roach, G. D., Garnham, A., Genders, A. J., Stokes, T., Schroder, E. A., & Huo, Z. (210101). Exercise mitigates sleep-loss-induced changes in glucose tolerance, mitochondrial function, sarcoplasmic protein synthesis, and diurnal rhythms. Molecular Metabolism, 43

doi: 10.1016/j.molmet.2020.101110

2020 Saner, N. J., & Lee, M. JC. (201101). Exercise: it's only a matter of time. Journal of Physiology, 598(21), (4755-4757).

doi: 10.1113/JP280366

Research funding for the past 5 years

Please note:

  • Funding is ordered by the year the project commenced and may continue over several years.
  • Funding amounts for contact research are not disclosed to maintain commercial confidentiality.
  • The order of investigators is not indicative of the role they played in the research project.

Exploring how carbohydrate intake and timing affect endurance adaptations and performance
From: Defence Science Institute
Other investigators: Aspr Andrew Garnham, Prof David Bishop
For period: 2021-2022
$15,000

Supervision of research students at VU

Available to supervise research students

Available for media queries

Currently supervised research students at VU

No. of students Study level Role
1 PhD Associate supervisor

Currently supervised research students at VU

Students & level Role
PhD (1) Associate supervisor

Careers

Details of this Researcher's career are currently unavailable.