Section: Overview
Overview
Key publications
Research funding
Supervising & teaching
Career

Key details

Areas of expertise

  • Sleep
  • Acute skeletal muscle responses to exercise
  • Sleep health
  • mitochondria
  • Exercise/muscle physiology

Available to supervise research students

Available for media queries

About Nicholas Saner

Dr Nicholas Saner is an early career researcher within the Institute for Health and Sport (IHES) at Victoria University. His research focuses on elucidating the mechanisms associated with the increased risk of chronic disease that occur with inadequate sleep and the influence of exercise intensity on skeletal muscle transcriptional responses and mitochondrial adaptations.

Nicholas completed his PhD at Victoria University in 2019 with the supervision of Prof. David Bishop and Dr Jonathan Bartlett. His thesis investigated the mechanisms underpinning reductions in glucose tolerance that occur with sleep loss and whether high-intensity interval exercise could counteract these effects.

Following his PhD, Nicholas accepted a post-doctoral research position at the Baker Heart and Diabetes Institute in the Human Integrated Physiology lab with A/Prof. Erin Howden and A/Prof Andre La Gerche. His research investigated the efficacy of a multi-faceted exercise intervention for preventing the adverse cardiovascular consequences of allogeneic stem cell transplantation, within the ALLO-Active clinical trial.

Dr Saner is currently supervising two PhD students and is the Deputy Chair of the early and mid-career researcher association at VU. He is also an ECR Editorial Board Member for The FASEB Journal and has contributed to sleep policy recommendations as part of the Sleep Health Expert Working Group with the Mitchell Institute. Nicholas has written articles for The Conversation, appeared on ABC radio, and talked on several scientific podcasts regarding his research.

Qualifications

  • PhD, Victoria University, 2019
  • Bachelor of Medical Research (Honours), University of Tasmania, 2014

Key publications

Year Citation
2024 Lee, M. JC., Saner, N. J., Ferri, A., Garcia-Dominguez, E., Broatch, J. R., & Bishop, D. J. (240601). Delineating the contribution of ageing and physical activity to changes in mitochondrial characteristics across the lifespan. Molecular Aspects of Medicine, 97

doi: 10.1016/j.mam.2024.101272

2024 Knowles, O. E., Soria, M., Saner, N. J., Trewin, A. J., Alexander, S. E., Roberts, S. SH., Hiam, D., Garnham, A. P., Drinkwater, E. J., & Aisbett, B. (240520). The interactive effect of sustained sleep restriction and resistance exercise on skeletal muscle transcriptomics in young females. Physiological Genomics,

doi: 10.1152/physiolgenomics.00010.2024

2024 Knowles, O. E., Soria, M., Saner, N. J., Trewin, A. J., Alexander, S. E., Roberts, S. SH., Hiam, D., Garnham, A. P., Drinkwater, E. J., & Aisbett, B. (240501). The interactive effect of sustained sleep restriction and resistance exercise on skeletal muscle transcriptomics in young females.. Physiological genomics,

doi: 10.1152/physiolgenomics.00010.2024

2024 Saner, N. J., Lee, M. JC., Pitchford, N. W., Broatch, J. R., Roach, G. D., Bishop, D. J., & Bartlett, J. D. (240401). The effect of sleep restriction, with or without high-intensity interval exercise, on behavioural alertness and mood state in young healthy males. Journal of Sleep Research, 33(2),

doi: 10.1111/jsr.13987

2024 Lee, M. J., Caruana, N. J., Saner, N. J., Kuang, J., Stokes, T., McLeod, J. C., Oikawa, S. Y., Bishop, D. J., Bartlett, J. D., & Phillips, S. M. (240101). Resistance-only and concurrent exercise induce similar myofibrillar protein synthesis rates and associated molecular responses in moderately active men before and after training. FASEB Journal, 38(1),

doi: 10.1096/fj.202302024R

2023 Bishop, D. J., Hoffman, N. J., Taylor, D. F., Saner, N. J., Lee, M. JC., & Hawley, J. A. (231101). Discordant skeletal muscle gene and protein responses to exercise. Trends in Biochemical Sciences, 48(11), (927-936).

doi: 10.1016/j.tibs.2023.08.005

2023 Genders, A. J., Kuang, J., Saner, N. J., Botella, J., & Bishop, D. J. (230101). Ammonium chloride administration prevents training-induced improvements in mitochondrial respiratory function in the soleus muscle of male rats. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 324(1), (C67-C75).

doi: 10.1152/ajpcell.00165.2022

2022 Dillon, H. T., Saner, N. J., Ilsley, T., Kliman, D., Spencer, A., Avery, S., Dunstan, D. W., Daly, R. M., Fraser, S. F., & Owen, N. (221201). Preventing the adverse cardiovascular consequences of allogeneic stem cell transplantation with a multi-faceted exercise intervention: the ALLO-Active trial protocol. BMC Cancer, 22(1),

doi: 10.1186/s12885-022-09793-w

2022 Lin, W., Saner, N. J., Weng, X., Caruana, N. J., Botella, J., Kuang, J., Lee, M. JC., Jamnick, N. A., Pitchford, N. W., & Garnham, A. (220722). The Effect of Sleep Restriction, With or Without Exercise, on Skeletal Muscle Transcriptomic Profiles in Healthy Young Males. Frontiers in Endocrinology, 13

doi: 10.3389/fendo.2022.863224

2022 Costello, B. T., Climie, R. E., Wright, L., Janssens, K., Mitchell, A., Wallace, I., Lindqvist, A., Foulkes, S., Paratz, E. D., & Flannery, M. D. (220401). Athletes with mild COVID-19 illness demonstrate subtle imaging abnormalities without exercise impairment or arrhythmias. European Journal of Preventive Cardiology, 29(6), (e220-e223).

doi: 10.1093/eurjpc/zwab166

Research funding for the past 5 years

Please note:

  • Funding is ordered by the year the project commenced and may continue over several years.
  • Funding amounts for contact research are not disclosed to maintain commercial confidentiality.
  • The order of investigators is not indicative of the role they played in the research project.

Exercise to counteract the negative effects of sleep loss on glycaemic control in women
From: Victoria University, Victorian Medical Research Acceleration Fund
Other investigators: Dr Nikeisha Caruana, Prof David Bishop, Dr Jujiao Kuang
For period: 2023-2024
$60,367

Supervision of research students at VU

Available to supervise research students

Available for media queries

Currently supervised research students at VU

No. of students Study level Role
2 PhD Associate supervisor

Currently supervised research students at VU

Students & level Role
PhD (2) Associate supervisor

Key academic roles

Dates Role Department / Organisation
Nov 2019 - Mar 2022
Post-doctoral researcher
Baker Heart and Diabetes Institute
Dates Role & Department/Organisation
Nov 2019 -
Mar 2022
Post-doctoral researcher
Baker Heart and Diabetes Institute

Awards

Year Award
2018

Young Investigator Award (Exercise and Health) - Exercise and Sport Science Australia

2020

Vice-Chancellor's Citation for Excellence in Research (Graduate Researcher) - Victoria University

Keynote and invited speeches

Year Title/Description
2018

Can exercise prevent the negative metabolic effects associated with sleep loss?

Invited presentation at the European College of Sport Science Conference, Dublin

2020

The Effect of Sleep Restriction, With or Without High-Intensity Exercise, on Myofibrillar Protein Synthesis in Healthy Young Men

Invited panel member, Virtual Journal Club - The Journal of Physiology and The Physiological Society